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Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals

BACKGROUND: Advances in whole genome sequencing have enabled the investigation of rare variants, which could explain some of the missing heritability that genome-wide association studies are unable to detect. Most methods to detect associations with rare variants are developed for unrelated individu...

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Vydáno v:BMC Proc
Hlavní autoři: Darst, Burcu F., Engelman, Corinne D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133523/
https://ncbi.nlm.nih.gov/pubmed/27980637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0031-z
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