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Prioritization of family member sequencing for the detection of rare variants

BACKGROUND: The advent of affordable sequencing has enabled researchers to discover many variants contributing to disease, including rare variants. There are methods for determining the most informative individuals for sequencing, but the application of these methods is more complex when working wit...

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Detalles Bibliográficos
Publicado en:BMC Proc
Main Authors: Sippy, Rachel, Kolesar, Jill M, Darst, Burcu F, Engelman, Corinne D
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133500/
https://ncbi.nlm.nih.gov/pubmed/27980641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0035-8
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