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Successful identification of rare variants using oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies
We aim to identify rare variants that have large effects on trait variance using a cost-efficient strategy. We use an oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies to identify families more likely to harbor rare variants, by estimating the mean number of q...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287833/ https://ncbi.nlm.nih.gov/pubmed/22373114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S11 |
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