Loading...

A general method for combining different family-based rare-variant tests of association to improve power and robustness of a wide range of genetic architectures

Current rare-variant, gene-based tests of association often suffer from a lack of statistical power to detect genotype–phenotype associations as a result of a lack of prior knowledge of genetic disease models combined with limited observations of extremely rare causal variants in population-based sa...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:BMC Proc
Main Authors: Green, Alden, Cook, Kaitlyn, Grinde, Kelsey, Valcarcel, Alessandra, Tintle, Nathan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133502/
https://ncbi.nlm.nih.gov/pubmed/27980630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0024-y
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!