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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies

Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...

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Bibliografiska uppgifter
I publikationen:Cancer Sci
Huvudupphovsmän: Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132279/
https://ncbi.nlm.nih.gov/pubmed/27554046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13062
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