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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies

Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132279/
https://ncbi.nlm.nih.gov/pubmed/27554046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13062
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