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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies

Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132279/
https://ncbi.nlm.nih.gov/pubmed/27554046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13062
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