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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies

Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...

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Библиографические подробности
Опубликовано в: :Cancer Sci
Главные авторы: Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132279/
https://ncbi.nlm.nih.gov/pubmed/27554046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13062
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