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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies

Histone deacetylases (HDACs) critically regulate gene expression by determining the acetylation status of histones. Studies have increasingly focused on the activities of HDACs, especially involving non‐histone proteins, and their various biological effects. Aberrant HDAC expression observed in seve...

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Dades bibliogràfiques
Publicat a:Cancer Sci
Autors principals: Imai, Yoichi, Maru, Yoshiro, Tanaka, Junji
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132279/
https://ncbi.nlm.nih.gov/pubmed/27554046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13062
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