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Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies and Solid Tumors

The human genome is epigenetically organized through a series of modifications to the histone proteins that interact with the DNA. In cancer, many of the proteins that regulate these modifications can be altered in both function and expression. One example of this is the family of histone deacetylas...

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Detalhes bibliográficos
Main Authors: Federico, Mario, Bagella, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004414/
https://ncbi.nlm.nih.gov/pubmed/21188171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/475641
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