Загрузка...

Evaluation of the Effect of Tofacitinib on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Volunteers

Tofacitinib is an oral Janus kinase inhibitor. Tofacitinib metabolism is primarily mediated by cytochrome P450 3A4. This phase 1 randomized, open‐label, 2‐way crossover study (NCT01137708) evaluated the effect of tofacitinib 30 mg twice daily on the single‐dose pharmacokinetics of combination oral c...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Clin Pharmacol Drug Dev
Главные авторы: Menon, Sujatha, Riese, Richard, Wang, Ronnie, Alvey, Christine W., Shi, Haihong, Petit, Wendy, Krishnaswami, Sriram
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132016/
https://ncbi.nlm.nih.gov/pubmed/27138968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.270
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!