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Protein Neddylation: Beyond Cullin-RING Ligases
NEDD8 is a ubiquitin-like protein that activates the largest ubiquitin E3 ligase family, the cullin RING ligases. Many non-cullin neddylation targets have been proposed in recent years. However, overexpression of exogenous NEDD8 can trigger NEDD8 conjugation through the ubiquitylation machinery, whi...
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| Udgivet i: | Nat Rev Mol Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131867/ https://ncbi.nlm.nih.gov/pubmed/25531226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3919 |
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