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Genome-Editing Technologies: Principles and Applications

Targeted nucleases have provided researchers with the ability to manipulate virtually any genomic sequence, enabling the facile creation of isogenic cell lines and animal models for the study of human disease, and promoting exciting new possibilities for human gene therapy. Here we review three foun...

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Pubblicato in:Cold Spring Harb Perspect Biol
Autori principali: Gaj, Thomas, Sirk, Shannon J., Shui, Sai-lan, Liu, Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131771/
https://ncbi.nlm.nih.gov/pubmed/27908936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023754
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