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Genome-Editing Technologies: Principles and Applications

Targeted nucleases have provided researchers with the ability to manipulate virtually any genomic sequence, enabling the facile creation of isogenic cell lines and animal models for the study of human disease, and promoting exciting new possibilities for human gene therapy. Here we review three foun...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Biol
Main Authors: Gaj, Thomas, Sirk, Shannon J., Shui, Sai-lan, Liu, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131771/
https://ncbi.nlm.nih.gov/pubmed/27908936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023754
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