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ML418: The first selective, sub-micromolar pore blocker of Kir7.1 potassium channels

The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) has recently emerged as a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. The pharmacological tools available for exploring the physiology and the...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Swale, Daniel R., Kurata, Haruto, Kharade, Sujay V., Sheehan, Jonathan, Raphemot, Rene R., Voigtritter, Karl R., Figueroa, Eric, Meiler, Jens, Blobaum, Anna L., Lindsley, Craig W., Hopkins, Corey R., Denton, Jerod S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131535/
https://ncbi.nlm.nih.gov/pubmed/27184474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00111
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