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A human FSHB transgene encoding the double N-glycosylation mutant (Asn(7Δ) Asn(24Δ)) FSHβ subunit fails to rescue Fshb null mice
Follicle-stimulating hormone (FSH) is a gonadotrope-derived heterodimeric glycoprotein. Both the common α- and hormone-specific β subunits contain Asn-linked N-glycan chains. Recently, macro-heterogeneous FSH glycoforms consisting of β-subunits that differ in N-glycan number were identified in pitui...
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| Publicado no: | Mol Cell Endocrinol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5130991/ https://ncbi.nlm.nih.gov/pubmed/26911932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.02.015 |
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