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Evaluation of in vivo bioactivities of recombinant hypo- (FSH(21/18)) and fully- (FSH(24)) glycosylated human FSH glycoforms in Fshb null mice

The hormone - specific FSHβ subunit of the human FSH heterodimer consists of N-linked glycans at Asn(7) and Asn(24) residues that are co-translationally attached early during subunit biosynthesis. Differences in the number of N-glycans (none, one or two) on the human FSHβ subunit contribute to macro...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Endocrinol
Autori principali: Wang, Huizhen, May, Jacob, Butnev, Viktor, Shuai, Bin, May, Jeffrey V., Bousfield, George R., Kumar, T. Rajendra
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048586/
https://ncbi.nlm.nih.gov/pubmed/27561202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.08.031
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