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Rescue of abnormal phenotypes of the δ2 glutamate receptor-null mice by mutant δ2 transgenes
The δ2 glutamate receptor (GluRδ2) has a crucial role in cerebellar functions; disruption of GluRδ2 alleles in mice (δ2(−/−)) impairs synapse formation and long-term depression, which is thought to underlie motor learning in the cerebellum, and consequently leads to motor discoordination. However, i...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1299222/ https://ncbi.nlm.nih.gov/pubmed/15592450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400312 |
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