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Rescue of abnormal phenotypes of the δ2 glutamate receptor-null mice by mutant δ2 transgenes

The δ2 glutamate receptor (GluRδ2) has a crucial role in cerebellar functions; disruption of GluRδ2 alleles in mice (δ2(−/−)) impairs synapse formation and long-term depression, which is thought to underlie motor learning in the cerebellum, and consequently leads to motor discoordination. However, i...

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Detalhes bibliográficos
Main Authors: Hirai, Hirokazu, Miyazaki, Taisuke, Kakegawa, Wataru, Matsuda, Shinji, Mishina, Masayoshi, Watanabe, Masahiko, Yuzaki, Michisuke
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299222/
https://ncbi.nlm.nih.gov/pubmed/15592450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400312
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