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Ca(2+) permeability of the channel pore is not essential for the δ2 glutamate receptor to regulate synaptic plasticity and motor coordination
The δ2 glutamate receptor (GluRδ2) plays a crucial role in cerebellar functions; mice with a disrupted GluRδ2 gene (GluRδ2(−/−)) display impaired synapse formation and abrogated long-term depression (LTD). However, the mechanisms by which GluRδ2 functions have remained unclear. Because a GluRδ2 muta...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Science Inc
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151382/ https://ncbi.nlm.nih.gov/pubmed/17255161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.127100 |
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