Ca(2+) permeability of the channel pore is not essential for the δ2 glutamate receptor to regulate synaptic plasticity and motor coordination

The δ2 glutamate receptor (GluRδ2) plays a crucial role in cerebellar functions; mice with a disrupted GluRδ2 gene (GluRδ2(−/−)) display impaired synapse formation and abrogated long-term depression (LTD). However, the mechanisms by which GluRδ2 functions have remained unclear. Because a GluRδ2 muta...

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Bibliographic Details
Main Authors: Kakegawa, Wataru, Miyazaki, Taisuke, Hirai, Hirokazu, Motohashi, Junko, Mishina, Masayoshi, Watanabe, Masahiko, Yuzaki, Michisuke
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2007
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151382/
https://ncbi.nlm.nih.gov/pubmed/17255161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.127100
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