Differential Regulation of Synaptic Plasticity and Cerebellar Motor Learning by the C-Terminal PDZ-Binding Motif of GluRδ2

The δ2 glutamate receptor (GluRδ2) is predominantly expressed in Purkinje cells and plays crucial roles in cerebellar functions: GluRδ2(−/−) mice display ataxia and impaired motor learning. In addition, long-term depression (LTD) at parallel fiber (PF)–Purkinje cell synapses is abrogated, and synaps...

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Publicat a:J Neurosci
Autors principals: Kakegawa, Wataru, Miyazaki, Taisuke, Emi, Kyoichi, Matsuda, Keiko, Kohda, Kazuhisa, Motohashi, Junko, Mishina, Masayoshi, Kawahara, Shigenori, Watanabe, Masahiko, Yuzaki, Michisuke
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671576/
https://ncbi.nlm.nih.gov/pubmed/18256267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2553-07.2008
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