Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases

Eukaryotic protein kinases regulate most cellular functions by phosphorylating targeted protein substrates through a highly conserved catalytic core. In the active state, the catalytic core oscillates between open, intermediate, and closed conformations. Currently, the intramolecular interactions th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Meharena, Hiruy S., Fan, Xiaorui, Ahuja, Lalima G., Keshwani, Malik M., McClendon, Christopher L., Chen, Angela M., Adams, Joseph A., Taylor, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130182/
https://ncbi.nlm.nih.gov/pubmed/27902690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2000127
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados