Genomic Characterization of Metformin Hepatic Response

Metformin is used as a first-line therapy for type 2 diabetes (T2D) and prescribed for numerous other diseases. However, its mechanism of action in the liver has yet to be characterized in a systematic manner. To comprehensively identify genes and regulatory elements associated with metformin treatm...

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Udgivet i:PLoS Genet
Main Authors: Luizon, Marcelo R., Eckalbar, Walter L., Wang, Yao, Jones, Stacy L., Smith, Robin P., Laurance, Megan, Lin, Lawrence, Gallins, Paul J., Etheridge, Amy S., Wright, Fred, Zhou, Yihui, Molony, Cliona, Innocenti, Federico, Yee, Sook Wah, Giacomini, Kathleen M., Ahituv, Nadav
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130177/
https://ncbi.nlm.nih.gov/pubmed/27902686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006449
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