A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes

Expression quantitative trait locus (eQTL) studies in human liver are crucial for elucidating how genetic variation influences variability in disease risk and therapeutic outcomes and may help guide strategies to obtain maximal efficacy and safety of clinical interventions. Associations between expr...

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Publicado en:Clin Pharmacol Ther
Autores principales: Etheridge, Amy S., Gallins, Paul J., Jima, Dereje, Broadaway, K. Alaine, Ratain, Mark J., Schuetz, Erin, Schadt, Eric, Schroder, Adrian, Molony, Cliona, Zhou, Yihui, Mohlke, Karen L., Wright, Fred A., Innocenti, Federico
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816646/
https://ncbi.nlm.nih.gov/pubmed/31868224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1751
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