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Genomic Characterization of Metformin Hepatic Response

Metformin is used as a first-line therapy for type 2 diabetes (T2D) and prescribed for numerous other diseases. However, its mechanism of action in the liver has yet to be characterized in a systematic manner. To comprehensively identify genes and regulatory elements associated with metformin treatm...

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Publicat a:PLoS Genet
Autors principals: Luizon, Marcelo R., Eckalbar, Walter L., Wang, Yao, Jones, Stacy L., Smith, Robin P., Laurance, Megan, Lin, Lawrence, Gallins, Paul J., Etheridge, Amy S., Wright, Fred, Zhou, Yihui, Molony, Cliona, Innocenti, Federico, Yee, Sook Wah, Giacomini, Kathleen M., Ahituv, Nadav
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130177/
https://ncbi.nlm.nih.gov/pubmed/27902686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006449
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