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Occupancy of Dopamine D(3) and D(2) Receptors by Buspirone: A [(11)C]-(+)-PHNO PET Study in Humans

There is considerable interest in blocking the dopamine D(3) receptor (DRD(3)) versus the D(2) receptor (DRD(2)) to treat drug addiction. However, there are currently no selective DRD(3) antagonists available in the clinic. The anxiolytic drug buspirone has been proposed as a potential strategy as f...

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Bibliografische gegevens
Gepubliceerd in:Neuropsychopharmacology
Hoofdauteurs: Le Foll, Bernard, Payer, Doris, Di Ciano, Patricia, Guranda, Mihail, Nakajima, Shinichiro, Tong, Junchao, Mansouri, Esmaeil, Wilson, Alan A, Houle, Sylvain, Meyer, Jeff H, Graff-Guerrero, Ariel, Boileau, Isabelle
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130128/
https://ncbi.nlm.nih.gov/pubmed/26089182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.177
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