Occupancy of Dopamine D(3) and D(2) Receptors by Buspirone: A [(11)C]-(+)-PHNO PET Study in Humans

There is considerable interest in blocking the dopamine D(3) receptor (DRD(3)) versus the D(2) receptor (DRD(2)) to treat drug addiction. However, there are currently no selective DRD(3) antagonists available in the clinic. The anxiolytic drug buspirone has been proposed as a potential strategy as f...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Le Foll, Bernard, Payer, Doris, Di Ciano, Patricia, Guranda, Mihail, Nakajima, Shinichiro, Tong, Junchao, Mansouri, Esmaeil, Wilson, Alan A, Houle, Sylvain, Meyer, Jeff H, Graff-Guerrero, Ariel, Boileau, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130128/
https://ncbi.nlm.nih.gov/pubmed/26089182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.177
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