Occupancy of Dopamine D(3) and D(2) Receptors by Buspirone: A [(11)C]-(+)-PHNO PET Study in Humans

There is considerable interest in blocking the dopamine D(3) receptor (DRD(3)) versus the D(2) receptor (DRD(2)) to treat drug addiction. However, there are currently no selective DRD(3) antagonists available in the clinic. The anxiolytic drug buspirone has been proposed as a potential strategy as f...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Le Foll, Bernard, Payer, Doris, Di Ciano, Patricia, Guranda, Mihail, Nakajima, Shinichiro, Tong, Junchao, Mansouri, Esmaeil, Wilson, Alan A, Houle, Sylvain, Meyer, Jeff H, Graff-Guerrero, Ariel, Boileau, Isabelle
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130128/
https://ncbi.nlm.nih.gov/pubmed/26089182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.177
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