Occupancy of Dopamine D(3) and D(2) Receptors by Buspirone: A [(11)C]-(+)-PHNO PET Study in Humans

There is considerable interest in blocking the dopamine D(3) receptor (DRD(3)) versus the D(2) receptor (DRD(2)) to treat drug addiction. However, there are currently no selective DRD(3) antagonists available in the clinic. The anxiolytic drug buspirone has been proposed as a potential strategy as f...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Le Foll, Bernard, Payer, Doris, Di Ciano, Patricia, Guranda, Mihail, Nakajima, Shinichiro, Tong, Junchao, Mansouri, Esmaeil, Wilson, Alan A, Houle, Sylvain, Meyer, Jeff H, Graff-Guerrero, Ariel, Boileau, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130128/
https://ncbi.nlm.nih.gov/pubmed/26089182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.177
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