Occupancy of Dopamine D(3) and D(2) Receptors by Buspirone: A [(11)C]-(+)-PHNO PET Study in Humans

There is considerable interest in blocking the dopamine D(3) receptor (DRD(3)) versus the D(2) receptor (DRD(2)) to treat drug addiction. However, there are currently no selective DRD(3) antagonists available in the clinic. The anxiolytic drug buspirone has been proposed as a potential strategy as f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropsychopharmacology
Prif Awduron: Le Foll, Bernard, Payer, Doris, Di Ciano, Patricia, Guranda, Mihail, Nakajima, Shinichiro, Tong, Junchao, Mansouri, Esmaeil, Wilson, Alan A, Houle, Sylvain, Meyer, Jeff H, Graff-Guerrero, Ariel, Boileau, Isabelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130128/
https://ncbi.nlm.nih.gov/pubmed/26089182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.177
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