The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer

Overexpression and/or hyperactivation of cyclin-dependent kinases (CDKs) are common features of most cancer types. CDKs have been shown to play important roles in tumor cell proliferation and growth by controlling cell cycle, transcription, and RNA splicing. CDK4/6 inhibitor palbociclib has been rec...

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Vydáno v:Oncotarget
Hlavní autoři: Zhou, Yubing, Shen, Jacson K., Hornicek, Francis J., Kan, Quancheng, Duan, Zhenfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130049/
https://ncbi.nlm.nih.gov/pubmed/27049727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8519
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