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Aberrant CDK9 expression within chordoma tissues and the therapeutic potential of a selective CDK9 inhibitor LDC000067

Objectives: Chordomas are slow-growing malignancies that commonly affect vital neurological structures. These neoplasms are highly resistant to current chemotherapeutic regimens and often recur after surgical intervention. Therefore, there is an urgent need to identify molecular targets and more rob...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Shen, Shen, Dean, Dylan C., Yu, Zujiang, Hornicek, Francis, Kan, Quancheng, Duan, Zhenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930393/
https://ncbi.nlm.nih.gov/pubmed/31892980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.35426
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