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Aberrant CDK9 expression within chordoma tissues and the therapeutic potential of a selective CDK9 inhibitor LDC000067

Objectives: Chordomas are slow-growing malignancies that commonly affect vital neurological structures. These neoplasms are highly resistant to current chemotherapeutic regimens and often recur after surgical intervention. Therefore, there is an urgent need to identify molecular targets and more rob...

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Dades bibliogràfiques
Publicat a:J Cancer
Autors principals: Shen, Shen, Dean, Dylan C., Yu, Zujiang, Hornicek, Francis, Kan, Quancheng, Duan, Zhenfeng
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930393/
https://ncbi.nlm.nih.gov/pubmed/31892980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.35426
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