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The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer

Overexpression and/or hyperactivation of cyclin-dependent kinases (CDKs) are common features of most cancer types. CDKs have been shown to play important roles in tumor cell proliferation and growth by controlling cell cycle, transcription, and RNA splicing. CDK4/6 inhibitor palbociclib has been rec...

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Publicat a:Oncotarget
Autors principals: Zhou, Yubing, Shen, Jacson K., Hornicek, Francis J., Kan, Quancheng, Duan, Zhenfeng
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130049/
https://ncbi.nlm.nih.gov/pubmed/27049727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8519
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