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Cyclin-dependent Kinase 11 (CDK11) is Required for Ovarian Cancer Cell Growth in vitro and in vivo, and its Inhibition Causes Apoptosis and Sensitizes Cells to Paclitaxel
Ovarian cancer is currently the most lethal gynecological malignancy with limited treatment options. Improved targeted therapies are needed to combat ovarian cancer. Here, we report the identification of cyclin-dependent kinase 11 (CDK11) as a mediator of tumor cell growth and proliferation in ovari...
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| Foilsithe in: | Mol Cancer Ther |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936930/ https://ncbi.nlm.nih.gov/pubmed/27207777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0032 |
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