Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads

Several compounds bearing the indolinone chemical scaffold are known to possess anticancer properties. For example, the tyrosine kinase inhibitor sunitinib is an arylideneindolin-2-one compound. The chemical versatility associated with structural modifications of indolinone compounds underlies the p...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Kaminska, Kamila K., Bertrand, Helene C., Tajima, Hisashi, Stafford, William C., Cheng, Qing, Chen, Wan, Wells, Geoffrey, Arner, Elias S.J., Chew, Eng-Hui
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130005/
https://ncbi.nlm.nih.gov/pubmed/27244886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9579
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