Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads

Several compounds bearing the indolinone chemical scaffold are known to possess anticancer properties. For example, the tyrosine kinase inhibitor sunitinib is an arylideneindolin-2-one compound. The chemical versatility associated with structural modifications of indolinone compounds underlies the p...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kaminska, Kamila K., Bertrand, Helene C., Tajima, Hisashi, Stafford, William C., Cheng, Qing, Chen, Wan, Wells, Geoffrey, Arner, Elias S.J., Chew, Eng-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130005/
https://ncbi.nlm.nih.gov/pubmed/27244886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9579
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