Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis

Midbrain dopaminergic (mDA) neurons are generated in the ventral midbrain floor plate depending on Sonic Hedgehog (SHH) signaling for induction. Primary cilia transduce canonical SHH signals. Loss of intraflagellar transport protein IFT88, essential for ciliary function, disrupts SHH signaling in th...

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Detalles Bibliográficos
Publicado en:Neurogenesis (Austin)
Main Authors: Gazea, Mary, Tasouri, Evangelia, Heigl, Tobias, Bosch, Viktoria, Tucker, Kerry L., Blaess, Sandra
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
Assuntos:
Brief Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129902/
https://ncbi.nlm.nih.gov/pubmed/28090543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23262133.2016.1248206
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