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Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis
Midbrain dopaminergic (mDA) neurons are generated in the ventral midbrain floor plate depending on Sonic Hedgehog (SHH) signaling for induction. Primary cilia transduce canonical SHH signals. Loss of intraflagellar transport protein IFT88, essential for ciliary function, disrupts SHH signaling in th...
שמור ב:
| הוצא לאור ב: | Neurogenesis (Austin) |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129902/ https://ncbi.nlm.nih.gov/pubmed/28090543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23262133.2016.1248206 |
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