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Allosteric regulation of Arf GTPases and their GEFs at the membrane interface

Arf GTPases assemble protein complexes on membranes to carry out major functions in cellular traffic. An essential step is their activation by guanine nucleotide exchange factors (GEFs), whose Sec7 domain stimulates GDP/GTP exchange. ArfGEFs form 2 major families: ArfGEFs with DCB, HUS and HDS domai...

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Publicat a:Small GTPases
Autors principals: Nawrotek, Agata, Zeghouf, Mahel, Cherfils, Jacqueline
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129899/
https://ncbi.nlm.nih.gov/pubmed/27449855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1215778
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