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Allosteric regulation of Arf GTPases and their GEFs at the membrane interface

Arf GTPases assemble protein complexes on membranes to carry out major functions in cellular traffic. An essential step is their activation by guanine nucleotide exchange factors (GEFs), whose Sec7 domain stimulates GDP/GTP exchange. ArfGEFs form 2 major families: ArfGEFs with DCB, HUS and HDS domai...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Nawrotek, Agata, Zeghouf, Mahel, Cherfils, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129899/
https://ncbi.nlm.nih.gov/pubmed/27449855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1215778
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