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Allosteric regulation of Arf GTPases and their GEFs at the membrane interface

Arf GTPases assemble protein complexes on membranes to carry out major functions in cellular traffic. An essential step is their activation by guanine nucleotide exchange factors (GEFs), whose Sec7 domain stimulates GDP/GTP exchange. ArfGEFs form 2 major families: ArfGEFs with DCB, HUS and HDS domai...

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Publicado en:Small GTPases
Autores principales: Nawrotek, Agata, Zeghouf, Mahel, Cherfils, Jacqueline
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129899/
https://ncbi.nlm.nih.gov/pubmed/27449855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1215778
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