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Allosteric regulation of Arf GTPases and their GEFs at the membrane interface

Arf GTPases assemble protein complexes on membranes to carry out major functions in cellular traffic. An essential step is their activation by guanine nucleotide exchange factors (GEFs), whose Sec7 domain stimulates GDP/GTP exchange. ArfGEFs form 2 major families: ArfGEFs with DCB, HUS and HDS domai...

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Foilsithe in:Small GTPases
Main Authors: Nawrotek, Agata, Zeghouf, Mahel, Cherfils, Jacqueline
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129899/
https://ncbi.nlm.nih.gov/pubmed/27449855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1215778
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