Bortezomib alleviates experimental pulmonary hypertension by regulating intracellular calcium homeostasis in PASMCs

The ubiquitin-proteasome system is considered to be the key regulator of protein degradation. Bortezomib (BTZ) is the first proteasome inhibitor approved by the US Food and Drug Administration for treatment of relapsed multiple myeloma and mantle cell lymphoma. Recently, BTZ treatment was reported t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Zhang, Jun, Lu, Wenju, Chen, Yuqin, Jiang, Qian, Yang, Kai, Li, Meichan, Wang, Ziyi, Duan, Xin, Xu, Lei, Tang, Haiyang, Sun, Dejun, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129762/
https://ncbi.nlm.nih.gov/pubmed/27413173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00324.2015
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