Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells

Cells in homeostasis metabolize glucose mainly through the tricarboxylic acid cycle and oxidative phosphorylation, while activated cells switch their basal metabolism to aerobic glycolysis. In this study, we examined whether metabolic reprogramming toward aerobic glycolysis is important for the host...

詳細記述

保存先:
書誌詳細
出版年:Eur J Immunol
主要な著者: Lachmandas, Ekta, Beigier‐Bompadre, Macarena, Cheng, Shih‐Chin, Kumar, Vinod, van Laarhoven, Arjan, Wang, Xinhui, Ammerdorffer, Anne, Boutens, Lily, de Jong, Dirk, Kanneganti, Thirumala‐Devi, Gresnigt, Mark S., Ottenhoff, Tom H.M., Joosten, Leo A.B., Stienstra, Rinke, Wijmenga, Cisca, Kaufmann, Stefan H.E., van Crevel, Reinout, Netea, Mihai G.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
Immunity to infection
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129526/
https://ncbi.nlm.nih.gov/pubmed/27624090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546259
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料