Lack of Adrenomedullin Results in Microbiota Changes and Aggravates Azoxymethane and Dextran Sulfate Sodium-Induced Colitis in Mice

The link between intestinal inflammation, microbiota, and colorectal cancer is intriguing and the potential underlying mechanisms remain unknown. Here we evaluate the influence of adrenomedullin (AM) in microbiota composition and its impact on colitis with an inducible knockout (KO) mouse model for...

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Udgivet i:Front Physiol
Main Authors: Martínez-Herrero, Sonia, Larrayoz, Ignacio M., Narro-Íñiguez, Judit, Villanueva-Millán, María J., Recio-Fernández, Emma, Pérez-Matute, Patricia, Oteo, José A., Martínez, Alfredo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127798/
https://ncbi.nlm.nih.gov/pubmed/27965594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00595
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