Antibiotics suppress colon tumorigenesis through inhibition of aberrant DNA methylation in an azoxymethane and dextran sulfate sodium colitis model

Chronic inflammation is involved in the development of colon cancer by inducing mutations and aberrant DNA methylation in colon epithelial cells. Furthermore, there is growing evidence that colonic microbiota modulates the inflammation response in the host and influences colon tumorigenesis. However...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Autores principales: Hattori, Naoko, Niwa, Tohru, Ishida, Tatsuya, Kobayashi, Kyosuke, Imai, Toshio, Mori, Akiko, Kimura, Kana, Mori, Takeshi, Asami, Yukio, Ushijima, Toshikazu
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317928/
https://ncbi.nlm.nih.gov/pubmed/30443963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13880
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