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Small molecules related to adrenomedullin reduce tumor burden in a mouse model of colitis-associated colon cancer

To investigate the contribution of adrenomedullin (AM) and its gene-related peptide, proadrenomedullin N-terminal 20 peptide (PAMP), to the progression and potential treatment of colon cancer we studied the effects of four small molecules (SM) related to AM and PAMP on a mouse model of colon cancer....

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Publicat a:Sci Rep
Autors principals: Ochoa-Callejero, Laura, García-Sanmartín, Josune, Martínez-Herrero, Sonia, Rubio-Mediavilla, Susana, Narro-Íñiguez, Judit, Martínez, Alfredo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727507/
https://ncbi.nlm.nih.gov/pubmed/29235493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17573-x
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