Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration

Retinitis pigmentosa (RP) encompasses a diverse group of Mendelian disorders leading to progressive degeneration of rods and then cones. For reasons that remain unclear, diseased RP photoreceptors begin to deteriorate, eventually leading to cell death and, consequently, loss of vision. Here, we have...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Zhang, Lijuan, Du, Jianhai, Justus, Sally, Hsu, Chun-Wei, Bonet-Ponce, Luis, Wu, Wen-Hsuan, Tsai, Yi-Ting, Wu, Wei-Pu, Jia, Yading, Duong, Jimmy K., Mahajan, Vinit B., Lin, Chyuan-Sheng, Wang, Shuang, Hurley, James B., Tsang, Stephen H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127684/
https://ncbi.nlm.nih.gov/pubmed/27841758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86905
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