Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration

Retinitis pigmentosa (RP) encompasses a diverse group of Mendelian disorders leading to progressive degeneration of rods and then cones. For reasons that remain unclear, diseased RP photoreceptors begin to deteriorate, eventually leading to cell death and, consequently, loss of vision. Here, we have...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Zhang, Lijuan, Du, Jianhai, Justus, Sally, Hsu, Chun-Wei, Bonet-Ponce, Luis, Wu, Wen-Hsuan, Tsai, Yi-Ting, Wu, Wei-Pu, Jia, Yading, Duong, Jimmy K., Mahajan, Vinit B., Lin, Chyuan-Sheng, Wang, Shuang, Hurley, James B., Tsang, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127684/
https://ncbi.nlm.nih.gov/pubmed/27841758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86905
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