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Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration

Retinitis pigmentosa (RP) encompasses a diverse group of Mendelian disorders leading to progressive degeneration of rods and then cones. For reasons that remain unclear, diseased RP photoreceptors begin to deteriorate, eventually leading to cell death and, consequently, loss of vision. Here, we have...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhang, Lijuan, Du, Jianhai, Justus, Sally, Hsu, Chun-Wei, Bonet-Ponce, Luis, Wu, Wen-Hsuan, Tsai, Yi-Ting, Wu, Wei-Pu, Jia, Yading, Duong, Jimmy K., Mahajan, Vinit B., Lin, Chyuan-Sheng, Wang, Shuang, Hurley, James B., Tsang, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127684/
https://ncbi.nlm.nih.gov/pubmed/27841758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86905
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