Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration

Retinitis pigmentosa (RP) encompasses a diverse group of Mendelian disorders leading to progressive degeneration of rods and then cones. For reasons that remain unclear, diseased RP photoreceptors begin to deteriorate, eventually leading to cell death and, consequently, loss of vision. Here, we have...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Zhang, Lijuan, Du, Jianhai, Justus, Sally, Hsu, Chun-Wei, Bonet-Ponce, Luis, Wu, Wen-Hsuan, Tsai, Yi-Ting, Wu, Wei-Pu, Jia, Yading, Duong, Jimmy K., Mahajan, Vinit B., Lin, Chyuan-Sheng, Wang, Shuang, Hurley, James B., Tsang, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127684/
https://ncbi.nlm.nih.gov/pubmed/27841758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86905
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