MicroRNA-29b mediates altered innate immune development in acute leukemia

Natural killer (NK) cells can have potent antileukemic activity following haplo-mismatched, T cell–depleted stem cell transplantations for the treatment of acute myeloid leukemia (AML), but they are not successful in eradicating de novo AML. Here, we have used a mouse model of de novo AML to elucida...

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Vydáno v:J Clin Invest
Hlavní autoři: Mundy-Bosse, Bethany L., Scoville, Steven D., Chen, Li, McConnell, Kathleen, Mao, Hsiaoyin C., Ahmed, Elshafa H., Zorko, Nicholas, Harvey, Sophia, Cole, Jordan, Zhang, Xiaoli, Costinean, Stefan, Croce, Carlo M., Larkin, Karilyn, Byrd, John C., Vasu, Sumithira, Blum, William, Yu, Jianhua, Freud, Aharon G., Caligiuri, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127669/
https://ncbi.nlm.nih.gov/pubmed/27775550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85413
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