MicroRNA-29b mediates altered innate immune development in acute leukemia

Natural killer (NK) cells can have potent antileukemic activity following haplo-mismatched, T cell–depleted stem cell transplantations for the treatment of acute myeloid leukemia (AML), but they are not successful in eradicating de novo AML. Here, we have used a mouse model of de novo AML to elucida...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Mundy-Bosse, Bethany L., Scoville, Steven D., Chen, Li, McConnell, Kathleen, Mao, Hsiaoyin C., Ahmed, Elshafa H., Zorko, Nicholas, Harvey, Sophia, Cole, Jordan, Zhang, Xiaoli, Costinean, Stefan, Croce, Carlo M., Larkin, Karilyn, Byrd, John C., Vasu, Sumithira, Blum, William, Yu, Jianhua, Freud, Aharon G., Caligiuri, Michael A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127669/
https://ncbi.nlm.nih.gov/pubmed/27775550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85413
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