A progenitor cell expressing transcription factor RORγt generates all human innate lymphoid cell subsets

The current model of murine innate lymphoid cell (ILC) development holds that mouse ILCs are derived downstream of the common lymphoid progenitor through lineage-restricted progenitors. However, corresponding lineage-restricted progenitors in humans have yet to be discovered. Here we identified a pr...

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Publicado en:Immunity
Autores principales: Scoville, Steven D, Mundy-Bosse, Bethany L, Zhang, Michael H, Chen, Li, Zhang, Xiaoli, Keller, Karen A, Hughes, Tiffany, Chen, Luxi, Cheng, Stephanie, Bergin, Stephen M, Mao, Hsiaoyin C, McClory, Susan, Yu, Jianhua, Carson, William E, Caligiuri, Michael A, Freud, Aharon G
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893782/
https://ncbi.nlm.nih.gov/pubmed/27178467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.04.007
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