MicroRNA-29b mediates altered innate immune development in acute leukemia

Natural killer (NK) cells can have potent antileukemic activity following haplo-mismatched, T cell–depleted stem cell transplantations for the treatment of acute myeloid leukemia (AML), but they are not successful in eradicating de novo AML. Here, we have used a mouse model of de novo AML to elucida...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Mundy-Bosse, Bethany L., Scoville, Steven D., Chen, Li, McConnell, Kathleen, Mao, Hsiaoyin C., Ahmed, Elshafa H., Zorko, Nicholas, Harvey, Sophia, Cole, Jordan, Zhang, Xiaoli, Costinean, Stefan, Croce, Carlo M., Larkin, Karilyn, Byrd, John C., Vasu, Sumithira, Blum, William, Yu, Jianhua, Freud, Aharon G., Caligiuri, Michael A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127669/
https://ncbi.nlm.nih.gov/pubmed/27775550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85413
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