MicroRNA-29b mediates altered innate immune development in acute leukemia

Natural killer (NK) cells can have potent antileukemic activity following haplo-mismatched, T cell–depleted stem cell transplantations for the treatment of acute myeloid leukemia (AML), but they are not successful in eradicating de novo AML. Here, we have used a mouse model of de novo AML to elucida...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mundy-Bosse, Bethany L., Scoville, Steven D., Chen, Li, McConnell, Kathleen, Mao, Hsiaoyin C., Ahmed, Elshafa H., Zorko, Nicholas, Harvey, Sophia, Cole, Jordan, Zhang, Xiaoli, Costinean, Stefan, Croce, Carlo M., Larkin, Karilyn, Byrd, John C., Vasu, Sumithira, Blum, William, Yu, Jianhua, Freud, Aharon G., Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127669/
https://ncbi.nlm.nih.gov/pubmed/27775550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85413
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