Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors

PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is lethal cancer whose primary tumor is characterized by dense composition of cancer cells, stromal cells and extracellular matrix (ECM) composed largely of collagen. Within the PDAC tumor microenvironment, activated pancreatic stellate cells (PSC) ar...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Kang, Ya’an, Roife, David, Lee, Yeonju, Lv, Hailong, Suzuki, Rei, Ling, Jianhua, Rios Perez, Mayrim V., Li, Xinqun, Dai, BingBing, Pratt, Michael, Truty, Mark J., Chatterjee, Deyali, Wang, Huamin, Thomas, Ryan M., Wang, Yu, Koay, Eugene J, Chiao, Paul J., Katz, Matthew H., Fleming, Jason B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127652/
https://ncbi.nlm.nih.gov/pubmed/27126993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2780
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia