SMAD4 Regulates Cell Motility through Transcription of N-Cadherin in Human Pancreatic Ductal Epithelium

Expression of the cellular adhesion protein N-cadherin is a critical event during epithelial-mesenchymal transition (EMT). The SMAD4 protein has been identified as a mediator of transforming growth factor-β (TGF-β) superfamily signaling, which regulates EMT, but the mechanisms linking TGF-β signalin...

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Bibliographische Detailangaben
Hauptverfasser: Kang, Ya'an, Ling, Jianhua, Suzuki, Rei, Roife, David, Chopin-Laly, Xavier, Truty, Mark J., Chatterjee, Deyali, Wang, Huamin, Thomas, Ryan M., Katz, Matthew H., Chiao, Paul J., Fleming, Jason B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180072/
https://ncbi.nlm.nih.gov/pubmed/25264609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107948
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